Patricia Calarco, PhD, Professor
pat.calarco@ucsf.edu
Administrative Assistant: 415-476-1861

Early Mammalian Development

Our research program focuses on the development and differentiation of the early mammalian embryo. Using combined approaches of morphology, biochemistry and molecular biology I am involved in the following projects: (1) To characterize the mechanisms of meiotic and early mitotic cell division; (2) To study the role of cell-extracellular matrix adhesion receptors in implantation, in collaboration with Dr. Caroline Damsky, UCSF; and (3) To identify the gene encoding an oocyte cortical granule protein in collaboration with P. Talbot (UC-R).


Complete list of Publications/PubMed

Selected Publications

Calarco, P. Polarization of mitochondria in the unfertilized mouse oocyte. Develop. Genetics, 16:36-43, 1995.

Almeida, E., Sutherland, A., Calarco, P., Sonnenberg, A., Myles, D., Primakof, P., and White, J. Mouse egg integrin a6b1 functions as a sperm receptor. Cell 81:1095-1104, 1995.

Hoodbhoy, T., P. Dandekar, P. Calarco and P. Talbot. Is p75 an ubiquitous component of mammalian cortical granules (CG)? 1996. Molec. Biol. of the Cell 7:306a.

Calarco, P. Microtubule organizing centers are anchored to the cortex prior to oocyte meiotic matu ration. Microscopy and Microanalysis 3:237-8,1997.

Calarco, P. 2000. Centrosome precursors in the acentriolar mouse oocyte. Micros Res & Tech 49:428-434.

Calarco, P. 2000. Immunoprobe localization by correlative microscopy. Microscopy & Microanalysis 6:295-201.