Research Papers:

1.         Mostov, K.E., Kraehenbuhl, J.-P. and Blobel, G.  Receptor-mediated transcellular transport of immunoglobulin:  Synthesis of secretory component as multiple and larger transmembrane forms.  Proc. Natl. Acad. Sci. USA 77:7557-7561, 1980.

2.         Mostov, K.E., DeFoor, P., Fleischer, S. and Blobel, G.  Co-translational membrane integation of calcium pump protein without signal sequence cleavage.  Nature 292:87-88, 1981.

3.         Hemperly, J.J., Mostov, K.E. and Cunningham, B.  In vitro translation and processing of a precursor form of favin, a lectin from Vicia faba.  J. Biol. Chem. 257:7903-7909, 1982.

4.         Mostov, K.E. and Blobel, G.  A transmembrane precursor of secretory component:  The receptor for transcellular transport of polymeric immunoglobulins.  J. Biol. Chem. 257:11816-11821, 1982.

5.         Mostov, K.E.  A transmembrane precursor of secretory component.  Rockefeller University, Ph.D. Dissertation, 1983.

6.         Anderson, D.J., Mostov, K.E. and Blobel, G.  Mechanisms of integration for de novo synthesized polypeptides into membranes.  Signal recognition particle is required for the integration into microsomal membranes of calcium ATPase and of lens MP26 but not of cytochrome B5.  Proc. Natl. Acad. Sci. USA 80:7249-7253, 1983.

7.         Mostov, K.E., Friedlander, M.F. and Blobel, G.  The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains.  Nature 308:37-43, 1984.

8.         Deitcher, D.L., Neutra, M. and Mostov, K.E.  Functional expression of polymeric immunoglobulin receptor from cloned cDNA in fibroblasts.  J. Cell Biol. 102:911-919, 1986.

9.         Deitcher, D.L. and Mostov, K.E.  Alternate splicing of rabbit polymeric immunoglobulin receptor.  Mol. Cell Biol. 6:2712-2715, 1986.

10.       Mostov, K.E. and Deitcher, D.L.  Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA.  Cell 47:613-621, 1986.

11.       Mostov, K.E., de Bruyn Kops, A. and Deitcher, D.L.  Deletion of the cytoplasmic domain of the polymeric immunoglobulin receptor prevents basolateral localization and endocytosis.  Cell 47:359-364, 1986.

12.       Mostov, K.E., Breitfeld, P. and Harris, J.M.  An anchor-minus form of the polymeric immunoglobulin receptor is secreted predominantly apically in Madin-Darby canine kidney cells.  J. Cell Biol. 105:66-70, 1988.

13.       Simister, N.E. and Mostov, K.  An Fc receptor structurally related to MHC class I antigens.  Nature 337:184-187, 1989.

14.       Breitfeld, P., Harris, J. and Mostov, K.  Post-endocytotic sorting of the ligand for the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells.  J. Cell Biol., 109: 475-486, 1989.

15.       Simister, N. and Mostov, K. Cloning and expression of the neonatal rat intestinal Fc receptor, an MHC Class I antigen homologue. Cold Spring Harbor Symposium Quantitative Biology, 54:571-580, 1989.

16.       LeBivic, A., Sambuy, Y., Mostov, K. and Rodriguez-Boulan, E.  Vectorial targetting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. J. Cell Biol., 110: 1533-1539, 1990.

17.       Casanova, J.E., Breitfeld, P.P., Ross, S.A. and Mostov, K.E.  Phosphorylation is required for efficient transcytosis of the polymeric immunoglobulin receptor.  Science, 248: 742-745, 1990.

18.       Breitfeld, P.P., Casanova, J.E., McKinnon, W.C., and Mostov, K.E.  Deletions in the cytoplasmic domain of the polymeric immunoglobulin receptor differentially affect endocytotic rate and postendocytotic traffic.  J. Biol. Chem., 256:, 13750-13757, 1990.

19.       Breitfeld, P.P., McKinnon, W.E., and Mostov, K.E.  Effects of nocodazole on traffic to the apical and basolateral surfaces of polarized Madin-Darby canine kidney cells.  J. Cell Biol., 111: 2365-2374, 1990.

20.       Casanova, J.E., Apodaca, G., and Mostov, K.E.  An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor.  Cell, 66: 65-75, 1991.

21.       Casanova, J., Mishumi, Y., Ikehara, Y., Hubbard, A. and Mostov, K.E. Direct apical sorting of rat liver dipeptidyl peptidase IV expressed in MDCK cells.  J. Biol. Chem., 266:24428-24432, 1991.

22.       Okamoto, C., Shia, S.P., Bird, C., Mostov, K., and Roth, M. The cytoplasmic domain of the polymeric immunoglobulin receptor contains two internalization signals that are distinct from its basolateral sorting signal.  J. Biol. Chem., 267:9925-9932, 1992.

23.       Chang, M. P., Mallet, W. G., Mostov, K. E. and Brodsky, F. M. Adaptor self-aggregation, adaptor-receptor recognition and binding of -adaptin subunits to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits. EMBO J,.  112: 2169-2180, 1993.

24.       Lindstedt, R., Apodaca, G., Barondes, S.H., Mostov, K., and Leffler, H.  Apical secretion of a cytosolic protein by MDCK cells: evidence for polarized release of an endogenous lectin by a non-classical secretory pathway.  J. Biol. Chem., 268:11750-11757, 1993.

25.       Apodaca, G., B. Aroeti, K. Tang, and K. E. Mostov.  Brefeldin-A inhibits the delivery of the polymeric immunoglobulin receptor to the basolateral surface of MDCK cells. J. Biol. Chem., 268:20380-20385, 1993.

26.       Bomsel M, and Mostov K.E.  Possible role of both the  and  subunits of the heterotrimeric G protein, Gs, in transcytosis of the polymeric immunoglobulin receptor. J. Biol. Chem., 268:25824-25835, 1993.

27.       Apodaca, G. and Mostov, K.E.  Transcytosis of placental alkaline phosphatase-polymeric immunoglobulin receptor fusion proteins is regulated by mutations of Ser664. J. Biol. Chem., 268:23712-23719, 1993.

28.       Aroeti, B., Kosen, P. A., Kuntz, I. D., Cohen, F. E., and Mostov, K. E.  Mutational and secondary structural analysis of the basolateral sorting signal of the polymeric immunoglobulin receptor. J. Cell Biol., 23:1149-1160, 1993.

29.       Song, W., Bomsel, M., Casanova, J., Vaerman, J.-P. and Mostov, K.E.  Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA. Proc. Natl. Acad. Sci. USA., 91:163-166, 1994.

30.       Cardone, M.H., Smith, B.L., Song, W., Mochley-Rosen, D., and Mostov, K.E.  Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells.  J. Cell Biol., 124:717-727, 1994.

31.       Okamoto, C.T., Song, W.,  Bomsel, M., and Mostov, K.E.  Rapid internalization of the polymeric immunologlobulin receptor requires phosphorylated serine 726.  J. Biol. Chem., 269:15676-15682, 1994.

32.       Crepaldi, T., Pollack, A., Prat, M., Zborek, A., Mostov, K., and Comoglio, P.M.  Targeting of the SF/HGF receptor to the basolateral domain of polzarized epithelial cells.  J. Cell Biol., 125:313-320, 1994.

33.       Apodaca, G., Katz, K.A., and Mostov, K.E.  Receptor-mediated transcytosis of IgA in MDCK cells via apical recycling endosomes. J. Cell Biol.,  125: 67-86, 1994.

34.       Aroeti, B., and Mostov, K.E.  Polarized sorting of the polymeric immunoglobulin receptor in the exocytotic and endocytotic pathways is controlled by the same amino acids.  EMBO J., 13:2297-2304, 1994.

35.       Apodaca, G., Enrich, C., and Mostov, K.E.  The calmodulin antagonist, W-13, alters transcytosis, recycling, and the morphology of the endocytic pathway in MDCK cells.  J. Biol Chem., 269:19005-19013, 1994.

36.       Bonzelius, F., Herman, G.A., Cardone, M.H., Mostov, K.E., and Kelly, R.B.  The polymeric immunoglobulin receptor accumulates in specialized endosomes but not synaptic vesicles within the neurites of transfected neuroendocrine PC12 cells.  J. Cell Biol., 127:1603-1616, 1994.

37.       Song, W., Apodaca, G., and Mostov, K.  Transcytosis of the polymeric immunoglobulin receptor is regulated in multiple intracellular compartments.  J. Biol. Chem., 269:29474-29480, 1994.

38.       Apodaca, G., Bomsel, M., Lindstedt, R., Engel, J., Frank, D., Mostov, K.E., and Wiener-Kronish, J.  Characterization of Pseudomonas aeruginosa-induced MDCK cell injury:  glycosylation defective host cells are resistant to bacterial killing.  Infection and Immunity, 63:1541-1551, 1995.

39.       Ma, J. K.-C., Hiatt, A., Hein, M., Vine, N.D., Wang, F., Stabila, P., van Dolleweerd, C., Mostov, K., Lehner, T.  Generation and assembly of secretory antibodies in plants.  Science 268:716-719, 1995.

40.       Cardone, M. and Mostov, K.  Wortmannin inhibits transcytosis of dimergic IgA by the polymeric immunoglobulin receptor.  FEBS Lett., 376:74-76, 1995.

41.       Song, W., Vaerman, J.-P., and Mostov, K.E.  Dimeric and tetrameric IgA are transcytosed equally by the polymeric immunoglobulin receptor.  J. Immunology 155:715-721, 1995.

42.       Chapin, S.J., Enrich, C., Aroeti, B., Havel, R.J., and Mostov, K.E.  Calmodulin binds to the basolateral targeting signal of the polymeric immunoglobulin receptor.  J. Biol. Chem., 271:1336-1342, 1996.

43.       Apodaca, G., Cardone, M.H., Whiteheart, S.W., DasGupta, B.R., and Mostov, K.E.  Reconstitution of transcytosis in SLO-permeabilized MDCK cells:  existence of an NSF dependent fusion mechanism with the apical surface of MDCK cells.  EMBO J., 15:1471-1481, 1996.

44.       Cardone, M.H., Smith, B.L., Mennitt, P.A., Mochly-Rosen, D., Silver, R.B., and Mostov, K.E.  Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.  J. Cell Biol., 133:997-1005, 1996.

45.       Reich, V., Mostov, K., and Aroeti, B.  The basolateral sorting signal of the polymeric immunoglobulin receptor contains two functional domains.  J. Cell. Sci. 109:2133-2139, 1996.

46.       Low, S.-H., Chapin, S.J., Weimbs, T., Kömüves, L.G., Bennett, M.K., and Mostov, K.E.  Differential localization of syntaxin isoforms in polarized MDCK cells.  Mol. Biol. Cell, 7:2007-2018, 1996.

47.       Balkovetz, D.F., Pollack, A.L., and Mostov, K.E.  Hepatocyte growth factor alters the polarity of MDCK cell monolayers.  J. Biol. Chem., 272:3471-3477, 1997.

48.       Barth, A.I.M., Pollack, A.L., Altschuler, Y., Mostov, K.E., and Nelson, W.J.  NH2-terminal deletion of -catenin results in stable colocalization of mutant -catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion.  J. Cell Biol., 136:693-706, 1997.

49.       Fleiszig, S.M.J., Wiener-Kronish, J.P., Miyazaki, H., Vallas, V., Mostov, K., Kanda, D., Sawa, T., Yen, T.S.B., and Frank, D.W.  Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate to distinct genotypes at the loci encoding exoenzyme S.  Infect. Immun. 65:579-586, 1997.

50.       Weimbs, T., Low, S.-H., Chapin, S.J., Mostov, K.E., Bucher, P. and Hofmann, K.  A conserved domain is present in different families of vesicular fusion proteins:  A new superfamily.  Proc. Natl. Acad. Sci. USA, 94:3046-3051, 1997.

51.       Pollack, A.L., Barth, A.I.M., Altschuler, Y., Nelson, W.J., Mostov, K.E.  Dynamics of -catenin interactions with APC protein regulate epithelial tubulogenesis.  J. Cell Biol. 137:1651-1662, 1997.

52.       Kang, P.J. Hauser, A.R. Apodaca, G. Fleiszig, S.M.J. Wiener-Kronish, J. Mostov, K., and Engel, J.N.  Identification of Pseudomonas aeruginosa genes required for epithelial cell injury.  Mol. Microbiol. 24:1249-1262, 1997.

53.       Fleiszig, S.M.J., Evans, D.J., Do, N., Vallas, V., Shin, S., Mostov, K.E.  Epithelial cell polarity affects susceptibility to Pseudomonas aeruginosa invasion and cytotoxicity.  Infect. Immun.  65:2861-2867, 1997.

54.       Low, S.-H., Roche, P.A., Anderson, H.A., van IJzendoorn, S.C.D., Zhang, M., Mostov, K.E., and Weimbs, T.  Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells.  J. Biol. Chem. 273:3422-3430, 1998.

55.       Singer, K.L. and Mostov, K.E.  Dimerization of the polymeric immunoglobulin receptor controls its transcytotic trafficking.  Mol. Biol Cell, 9:901-915, 1998.

56.       Luton, F., Cardone, M.H., Zhang, M. and Mostov, K.E.  Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor.  Mol. Biol Cell 9:1787-1802, 1998.

57.       Hauser, A.R., Fleiszig, S., Kang, P.J., Mostov, K., and Engel, J.N.  Defects in Type III secretion correlate with internalization of Pseudomonas aeruginosa by epithelial cells.  Infect. Immun. 66:1413-1420, 1998.

58.       Fleiszig, S.M.J., Vallas, V., Jun, C.H., Mok, L., Balkovetz, D.F., Roth, M.G., and Mostov, K.E.  Susceptibility of epithelial cells to Pseudomonas aeruginosa invasion and cytotoxicity is upregulated by hepatocyte growth factor (HGF).  Infect. Immun. 66:3443-3446, 1998.

59.       Low, S.-H., Chapin, S.J., Wimmer, C., Whiteheart, S.W., Kómüves, L.G., Mostov, K.E., and Weimbs, T.  The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells.  J. Cell Biol. 141:1503-1513, 1998.

60.       Pollack, A.L., Runyan, R.B. and Mostov, K.E.  Morphogenetic mechanisms of epithelial tubulogenesis:  MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis.  Dev. Biol., 204:64-79, 1998

61.       Altschuler, Y., Barbas, S.M., Terlecky, L.J., Tang, K., Hardy, S., Mostov, K.E., and Schmid, S.L.  Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms.  J. Cell Biol., 143:1871-1881, 1998.

62.       Malmborg, A.-C., Shultz, D.B., Luton, F., Mostov, K.E., Richly, E., Leung, P.S.C., Benson, G.D., Ansari, A.A., Coppel, R.L., Gershwin, M.E., Van de Water, J.  Penetration and co-localization in MDCK cell mitochondria of IgA derived from patients with primary biliary cirrhosis.  J. Autoimmun., 11:573-580, 1998.

63.       Luton, F. and Mostov, K.E.  Transduction of basolateral-to-apical signals across epithelial cells: Ligand stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals.  Mol. Biol. Cell, 10:1409-1427, 1999.

64.       Comolli, J.C., Waite, L.L., Mostov, K.E., and Engel, J.N. Pili binding to asialo-GM1 on epithelial cells can mediate cytotoxicity or bacterial internalization by Pseudomonas aeruginosa. Infect. Immun., 67:3207-3214, 1999.

65.       Vergés, M., Havel, R.J. and Mostov, K.E. A tubular endosomal fraction from rat liver:Biochemical evidence of receptor sorting by default. Proc. Natl. Acad. Sci. USA. 96:10146-10151, 1999.

66.       Altschuler, Y., Liu, S.-H., Katz, L., Tang, K., Hardy, S., Brodsky, F., Apodaca, G., Mostov, K. ADP-ribosylation factor 6 and endocytosis at the apical surface of Madin-Darby canine kidney cells. J Cell Biol. 147:7-12, 1999.

67.       Luton, F., Vergés, M., Vaerman, J.-P., Sudol, M., and Mostov, K.E. The src family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo.  Mol. Cell. 4:627-632, 1999.

68.       Brown, P.S., Wang, E., Aroeti, B., Chapin, S.J., Mostov, K.E., and Dunn, K.W.  Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling.  Traffic 1:124-140, 2000.

69.       Zhang, W., Razani, B., Altschuler, Y., Bouzahzah, B., Mostov, K.E., Pestell, R.G., and Lisanti, M.P.  Caveolin-1 inhibits EGF-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3).  Transformation suppressor effects of adenoviral-mediated gene delivery of caveolin-1. J. Biol. Chem., 275:20717-20725, 2000.

70.       Wang, E., Brown, P.S., Aroeti, B., Chapin, S.J., Mostov, K.E., and Dunn, K.W.  Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome.  Traffic, 1:480-493, 2000.

71.       Van Ooij, C., Kalman, L., van IJzendoorn, S., Nishijima, M., Hantada, K., Mostov, K., and Engel, J.  Host-cell derived sphingolipids are required for the intracellular growth of Chlamydia trachomatis.  Cell. Microbiol., 2:627-638, 2000.

72.       Low, S.-H., Miura, M., Roche, P.A., Valdez, A.C., Mostov, K.E., and Weimbs, T.  Intracellular redirection of plasma membrane trafficking after loss of epithelial cell polarity.  Mol. Biol. Cell, 11:3045-3060, 2000.

73.       Zhang, J.-R., Mostov, K.E., Lamm, M.E., Nanno, M., Ohwaki, M., Shimada, S.-I., Ohwaki, M., and Tuomanen, E.  The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells.  Cell, 102:827-837, 2000.

74.       Lipschutz, J.H., Guo, W., O'Brien, L.E., Nguyen, Y.H., Novick, P., Mostov, K.E.  Exocyst is involved in cystogenesis and tubulogenesis and acts by modulating synthesis and delivery of basolateral plasma membrane and secretory proteins.  Mol. Biol. Cell, 11:4259-4275, 2000.

75.       Trejo, J., Altschuler, Y., Fu, H. W., Mostov, K. E., and Coughlin, S. R.  Protease-activated receptor-1 down-regulation. A mutant HeLa cell line suggests novel requirements for par1 phosphorylation and recruitment to clathrin-coated pits. J. Biol. Chem. 275:31255-31265,  2000.

76.       Razani, B., Altschuler, Y., Zhu, L., Pestell, R.G., Mostov, K.E., and Lisanti, M.P.  Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner.  Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.  Biochemistry 39:13916-13924,  2000.

77.       Hansen, S.H., Zegers, M.M.P., Woodrow, M., Rodriguez-Viciana, P., Chardin, P., Mostov, K.E., and McMahon, M.  Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway.  Mol. Cell. Biol. 20:9364-9375,  2000.

78.       Kazmierczak, B.I., Jou, T.S., Mostov, K., Engel, J.N. Rho GTPase activity modulates Pseudomonas aeruginosa internalization by epithelial cells.  Cell. Microbiol. 3:85-98, 2001.

79.       Mangravite, L.M., Lipschutz, J.H., Mostov, K.E., and Giacomini, K.M. Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line.  Am. J. Physiol. Renal Physiol. 280:F879-885, 2001.

80.       O’Brien, L.E., Jou, T.-S., Pollack, A.L., Zhang, Q., Hansen, S.H., Yurchenco, P., and Mostov, K.E. Rac1 orients epithelial apical polarity through effects on basolateral laminin assembly.  Nat. Cell Biol., 3:831-838, 2001.

81.       van IJzendoorn, S.C.D., Tuvim, M.J., Weimbs, T., Dickey, B.F., and Mostov, K.E.  Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells.  Develop. Cell, 2:219-228, 2002.

82.       Yu, W., O’Brien, L.E., Wang, F., Bourne, H., Mostov, K.E., and Zegers, M.M.P.  Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures.  Mol. Biol. Cell, 14:748-763, 2003.

83.       Lipschutz, J.H., Lingappa, V.R. and Mostov, K.E.  The exocyst affects protein synthesis by acting on the translocation machinery of the endoplasmic reticulum.  J. Biol. Chem, 278:20954-20960, 2003.

84.       Lai, J.-F., Juang, S.-H., Hung, Y.-M., Cheng, H.-Y., Cheng, T.-L., Mostov, K.E., and Jou, T.-S. An ecdysone and tetracycline dual regulatory expression system for studies on Rac1 small GTPase-mediated signaling.  Amer. J. Physiol., 285:C711-C719, 2003.

85.       Zegers, M.M.P., Forget, M.A., Chernoff, J., Mostov, K.E., ter Beest, M., Hansen, S.H.  PAK1 and PIX regulate contact inhibition during epithelial wound healing.  EMBO J., 22:4155-4165, 2003.

86.       Kazmierczak, B. I., Mostov, K.E., and Engel, J. N.  Epithelial cell polarity alters Rho-GTPase responses to Pseudomonas aeruginosa.  Molecular Biology of the Cell, 15:411-419, 2004.

87.       Matsumura, S., Van de Water, J., Leung P., Odin, J.A., Yamamoto, K., Gores, G.J., Mostov, K.E., Ansari, A., Coppel, R.L., Shiratori, Y., Gershwin, M.E.  Caspase induction by IgA antimitochondrial antibody:  IgA-mediated biliary injury in primary biliary cirrhosis.  Hepatology, 39:1415-1422, 2004.

88.       O'Brien, L.E., Tang., K., Kats E.S., Schutz-Geschwender, A., Lipschutz, J.A., Mostov, K.E., ERK and MMPs Sequentially regulate distinct stages of epithelial tubule development.  Developmental Cell, 07:21-32, 2004.

89.       Vergés,  M., Luton, F., Gruber, C., Tiemann,  F., Reinders, L., Huang, L., Burlingame, A., Haft, C.,  Mostov. K.E. The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor.  Nature Cell Biology, 06:763-769, 2004.

90.       Yu, W., Datta, A., Leroy, P., O'Brien, L.E., Mak, G., Jou, T.S., M, Matlin, K.S., Mostov, K.E., and Zegers, M.M.P.  1-integrin orients epithelial polarity via Rac1 and laminin.  Mol. Biol. Cell, 16:433-445, 2005.

91.       Tanimizu, N., Saito, H., Mostov, K., and Miyajima, A.  Long-term culture of hepatic progenitors derived from mouse Dlk+ hepatoblasts.  J. Cell Sci., 117:6425-6434,  2005.

92.       Kierbel, A., Gassama-Diagne, A., Mostov, K., and Engel, J.N. The Phosphoinositol-3-kinase-Protein kinase B/Akt  pathway is critical for Pseudomonas aeruginosa strain PAK internalization. Mol. Biol. Cell, 16:2577-2585, 2005.

93.       ter Beest,  M., Chapin, S. J., Avrahami, D., and Mostov, K. E.  The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells.  Mol. Biol. Cell, 16:5784-5792, 2005.

94.       Fan, Q., Knight, Z. A., Goldenberg, D. D., Yu, W., Mostov, K., Stokoe, D., Shokat, K. M., Weiss, W. A. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell, 9:341-349, 2006.

95.       Gassama, A, Yu, W., Martin, F., ter Beest, M., Kierbel, A, Engel, J., Mostov, K.  Phosphatidylinositol 3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells. Nat. Cell Biol 8:963-970, 2006.

96.       Grant, M., Mostov, K., Tlsty, T., Hunt, C. A., Simulating Properties of In Vitro Epithelial Cell Morphogenesis. PLoS Computational Biology  2: e129, 1-17, 2006

97.       Martin-Belmonte, F., Gassama, A., Datta, A., Yu. W., Rescher, U., Gerke, V., and Mostov, K.  PTEN-mediated apical segregation of phosphoinositides controls epithelial polarity through Cdc42.  Cell, 128:383-397, 2007.

Invited Reviews:

1.         Mostov, K.E. and Blobel, G.  Transcellular transport of polymeric immunoglobulins by secretory component:  A model system for studying intracellular protein sorting.  Annals N.Y. Acad. Sci. 409:441-451, 1983.

2.         Mostov, K.E. and Blobel, G.  Biosynthesis, processing, and function of secretory component.  Methods in Enzymology  98:458-466, 1983.

3.         Mostov, K.E., Deitcher, D.L., Friedlander, M.F. and Blobel, G.  Receptor-mediated transcellular transport of IgA and IgM.  In: Protein Transport and Secretion, M.J. Gething, ed., Cold Spring Harbor Laboratory.  1985.

4.         Mostov, K.E., Friedlander, M. and Blobel, G.  Structure and function of the receptor for polymeric immunoglobulins.  Biochem. Soc. Symp.  51:113-115, 1985.

5.         Mostov, K.E. and Simister, N.  Transcytosis.  Cell 43:389-390, 1985.

6.         Breitfeld, P., Harris, J.M. and Mostov, K.E.  Cell biology of the IgA receptor in polarized epithelia.  Mongr. Allergy 24:66-70, 1988.

7.         Breitfeld, P., Casanova, J.E., Harris, J.M., Simister, N.E. and Mostov, K.E.  Expression and analysis of the polymeric immunoglobulin receptor in MDCK cells using retroviral vectors.  Methods in Cell Biology, 32: 329-337, 1989.

8.         Breitfeld, P., Casanova, J.E., Ross, S.A., McKinnon, W. and Mostov, K.E.  Sorting signals.  Current Opinion in Cell Biology, 1:617-623, 1989.

9.         Breitfeld, P., Casanova, J.E., Simister, N.E., Ross, S.A., McKinnon, W. and Mostov, K.E.  Transepithelial transport of immunoglobulins: A model of protein sorting and transcytosis.  Amer. J. of Resp. Cell and Molec. Biol., 1:257-262, 1989.

10.       Apodaca, G., Bomsel, M., Arden, J., Breitfeld, P.P., Tang, K. and Mostov, K. The polymeric immunoglobulin receptor: A model protein to study transcytosis.  J. Clin. Inves., 87:1877-1882,1991.

11.       Bomsel, M. and Mostov, K.E.  Sorting of plasma membrane proteins in epithelial cells.  Cur. Op. Cell Biol., 3:647-653, 1991.

12.       Mostov, K.E.  The polymeric immunoglobulin receptor.  Seminars in Cell Biology, 2:411-418, 1991.

13.       Mostov, K.E., Apodaca, G., Aroeti, B., and Okamoto, C.  Plasma membrane protein sorting in polarized epithelial cells.  J. Cell Biol., 116:577-583, 1992.

14.       Aroeti, B., Casanova, J., Okamoto, C., Cardone, M., Pollack, A., Tang, K., and Mostov, K.  Polymeric immunoglobulin receptor. In: Molecular Biology of Receptors and Transporters Receptors.  M. Friedlander and M. Mueckler (eds.), Academic Press, Inc., New York, Vol. 137B, pp. 157-168, 1992.

15.       Bomsel, M. and Mostov, K.  Role of heterotrimeric G proteins in membrane traffic.  Molec. Biol. Cell, 3:1317-1328, 1992.

16.       Mostov, K.  The Polymeric Immunoglobulin Receptor.  In:  Hepatic Endocytosis of Lipids and Proteins, E. Windler, H. Greten, eds., W. Zuckschwerdt Verlag, Munich-Bern-Vienna-New York, 70-79, 1992.

17.       Hiatt, A. and Mostov, K.E.  Assembly of multimeric proteins in plant cells: characteristics and uses of plant-derived antibodies. In: Transgenic Plants: Fundamentals and Applications, A. Hiatt, ed., Marcel Dekker, Inc., New York, 221-237, 1993.

18.       Bonzelius, F., Herman, G.A., Cardone, M.H., Mostov, K.E. and Kelly, R.B.  Targeting of the polymeric immunoglobulin receptor in transfected PC12 cells.  In:  Molecular mechanisms of membrane traffic; D. J. Morré, J. J. M. Bergeron and K. M. Howell (eds.); NATO ASI Series H, Vol. 74; Springer-Verlag, Berlin, Heidelberg, New York; 203-204, (1993).

19.       Mostov, K.  Protein traffic in polarized epithelial cells:  the polymeric immunoglobulin receptor as a model system.  Journal of Cell Science, 17:21-26, 1993.

20.       Mostov, K.E.  Transepithelial transport of immunoglobulins.  Ann. Rev. Immunol., 12:63-84, 1994.

21.       Bomsel, M. and Mostov, K.E.  Both the Gs alpha and beta-gamma subunits of the heterotrimeric G protein Gs control the sorting of the polymeric immunoglobulin receptor into transcytotic vesicles.   Biochemical Society Transactions.  1994 May.  V22 N2:463-468.

22.       Mostov, K.E.  Regulation of protein traffic in polarized epithelial cells.  Histology and Histopathology, 10:423-431, 1995.

23.       Mostov, K.E. and Cardone, M.H.  Regulation of protein traffic in polarized epithelial cells.  BioEssays, 17:729-738, 1995.

24.       Mostov, K.E., Altschuler, Y., Chapin, S., Enrich, C., Low, S.-H., Luton, F., Richman-Eisenstat, J., Singer, K.L., Tang, K., and Weimbs, T.  Regulation of protein traffic in polarized epithelial cells: the polymeric immunoglobulin receptor model.  Cold Spring Harbor Symposium Quantitative Biology, 60:775-781, 1995.

25.       Enrich, C., Apodaca, G., and Mostov, K.E.  Calmodulin regulates the intracellular trafficking in epithelial cells.  Zeitschrift fur Gastroenterologie, 1996 Jun, 34 Suppl 3:83-85.

26.       Mostov, K., and Werb, Z.  Journey across the osteoclast.  Science, 276:219-220, 1997.

27.       Weimbs, T., Low, S.-H., Chapin, S.J., and Mostov, K.E.  Apical targeting in polarized epithelial cells:  there's more afloat than rafts.  Trends in Cell Biol. 7:393-399, 1997.

28.       Weimbs, T., Mostov, K.E., Low, S.-H., and Hofman, K.  A model for structural similarity between different SNARE complexes based on sequence relationships.  Trends Cell Biol. 8:260-262, 1998.

29.       Kaetzel, C. and Mostov, K.E.  The polymeric immunoglobulin receptor.  In:  The immunoglobulin receptors and their physiological and pathological roles in immunity, J.G.J. van de Winkel and P.M. Hogarth (eds.), Kluwer Academic Publishers, Dordrecht, Vol. 26, pp. 51-62, 1998.

30.       Mostov, K.E. and Kaetzel, C.  Immunoglobulin transport and the polymeric immunoglobulin receptor.  In:  Mucosal Immunology, P.L. Ogra, J. Mestecky, M.E. Lamm, W. Strober, J.R. McGhee, J. Bienenstock (eds.), Academic Press, Inc., New York, pp., 181-211, 1999.

31.       Mostov, K.E., ter Beest, M.B.A., and Chapin, S.J.  Catch the 1B train to the basolateral surface. Cell.  99:121-122, 1999.

32.       Mostov, K.E., Verges, M., and Altschuler, Y., Membrane traffic in polarized epithelial cells.  Curr. Op. Cell Biol. 12:483-490, 2000.

33.       Lipschutz, J.H., O’Brien, L.E., Altschuler, Y., Avrahami, D., Nguyen, Y., Tang, K., and Mostov, K.E.  Analysis of membrane traffic in polarized epithelial cells.  Curr. Protocols Cell Biol., 15.5, 2001.

34.       van IJzendoorn, S.C.D. and Mostov, K.E.  Connecting apical endocytosis to the intracellular traffic infrastructure in polarized hepatocytes.  Gastroenterology. 119:1791-1794, 2000.

35.       Kazmierczak, B.I., Mostov, K., and Engel, J.N.  Interaction of bacterial pathogens with polarized epithelium.  Annu. Rev. Microbiol. 55:407-435, 2001.

36.       O’Brien, L.E., and Mostov, K.E.  Getting from here to there.  Nat. Cell Biol. 3:E116, 2001.

37.       von Zastrow, M. and Mostov, K.  Signal transduction. A new thread in an intricate web.  Science.  294:1845-1847, 2001.

38.       Lipschutz, J.H. and Mostov, K.E.  Exocytosis:  The many masters of the exocyst.  Curr. Biol. 12:R212-R214, 2002.

39.       O’Brien, L.E., Zegers, M.M.P., and Mostov, K.E.  Opinion: Building epithelial architecture: insights from three-dimensional culture models.  Nat. Rev. Mol. Cell Biol. 3:531-537, 2002.

40.       Zegers, M.M.P., O’Brien, L.E., Yu, W., Datta, A., and Mostov, K.E. Epithelial polarity and tubulogenesis in vitro.  Trends Cell Biol., 13:169-176, 2003

41.       Mostov, K.E. and Zegers, M.M.P. Just mix and patch.  Nature, 422:267-268, 2003.

42.       Mostov, K.E.  Epithelial polarity and morphogenesis.  Methods, 30:189-190, 2003.

43.       Mostov, K., Su, T., ter Beest, M.  Polarized epithelial membrane traffic: conservation and plasticity. Nat Cell Biol. 5:287-293, 2003.

44.       Mostov K, Brakeman P, Datta A, Gassama A, Katz L, Kim M, Leroy P, Levin M, Liu K, Martin F, O'Brien LE, Verges M, Su T, Tang K, Tanimizu N, Yamaji T, Yu W.  Formation of multicellular epithelial structures.  Novartis Found Symp, 269:193-20, 2005.

45.       O’Brien, L.E., Yu, W., Tang, K., Jou, T.-S., Zegers, M.M.P., and Mostov, K.E.  Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures.  Methods in Enzymology,  406:676-691, 2006.

46.       Mostov, K. mTOR is out of control in polycystic kidney disease. PNAS 103:5247-8, 2006.
 
47.       Mostov, K. and Martin-Belmonte, F.  The hole picture.  Nature 442: 363-4.

48.       Reiter, J. and Mostov, K.,  Vesicle transport, cilium formation and membrane specialization: The origins of a sensory organelle.  Proc. Natl. Acad. Sci. USA, in press