“Many cancers either fail to respond to a single targeted therapy or acquire resistance after initially responding. The notion that combining targeted therapies is a far more effective way to treat cancer than a single-drug approach has long existed. We wanted to perform screens with saturating coverage to understand exactly what combinations should be explored,”
-Jeroen Roose PhD, professor of anatomy and senior author of the new study.
Jeroen Roose along with Co-Author Michael T. McManus, PhD, professor at the UCSF Diabetes Center published this in a study in the jorunal Cell Reports
Read the UCSF Press Release here