Anatomy Department

slider cell image
pancreatic cancer cells have abundant autophagosomes
slider cell image
immunohistochemistry of patient pancreatic ductal adenocarinoma for the transcription factor TFE3 organoids : pancreatic tumor organoids grown in culture
slider cell image
Injury-activated microglia (red) in close proximity to inhibitory synapses (green) in the dorsal spinal cord
slider cell image
Activated microglia (green with red nuclei) surrounding an injured motoneuron (blue) in the mouse spinal cord

Cancer-Killing Combination Therapies Unveiled with New Drug-Screening Tool

UCSF News Center…

“Many cancers either fail to respond to a single targeted therapy or acquire resistance after initially responding. The notion that combining targeted therapies is a far more effective way to treat cancer than a single-drug approach has long existed. We wanted to perform screens with saturating coverage to understand exactly what combinations should be explored,”

-Jeroen Roose PhD, professor of anatomy and senior author of the new study.

Jeroen Roose along with Co-Author Michael T. McManus, PhD, professor at the UCSF Diabetes Center published this in a study in the jorunal Cell Reports

Read the UCSF Press Release here

Roose Lab Homepage