2008
Lu, P., A. J. Ewald, G. R. Martin & Z. Werb (2008). Genetic mosaic analysis reveals FGF receptor 2 is required in terminal end buds during mammary gland branching morphogenesis. Dev. Biol. In press. doi:10.1016/j.ydbio.2008.06.005.
Nielsen, B. S., M. Egeblad, F. Rank, H. A. Askautrud, C. Pennington, D. Edwards, I. J. Christensen, Z. Werb & L. R. Lund (2008). Matrix metalloproteinase 13 is induced in myofibroblasts in early invasive polyoma middle T oncogene-induced breast cancer, but does not affect tumor progression or metastasis. PLoS One. Accepted subject to minor revisions.
*Egeblad, M., A. J. Ewald, H. A. Askautrud, B. E. Welm, M. Truitt, E. Bainbridge, G. Peeters, M. Krummell & Z. Werb (2008). Imaging stromal cell behavior in intact tumor microenvironments. Disease Models Mech. In press.
Riedl, J., A. Crevenna, K. Kessenbrock, J. H. Yu, D. Neukirchen, M. Bista, F. Bradke, D. Jenne, T. Holak, Z. Werb, M. Sixt & R. Wedlich-Soldner (2008). Lifeact - a versatile marker to visualize F-actin. Nature Meth. [Epub ahead of print 2008 Jun 8]. PMID: 18536722 PDF
Martín-Belmonte, F., W. Yu, A. E. Rodríguez-Fraticelli, A. J. Ewald, Z. Werb, M. A. Alonso & K. Mostov (2008). Cell polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis. Curr. Biol.PDF
Adler, A.S., L. E. Littlepage et al. (2008). Essential role of CSN5 isopeptidase activity in breast cancer progression. Cancer Res. 68: 506-515. PMID: 18199546 PDF
Du, R., K. Lu, et al. (2008). HIF1a promotes tumor progression by inducing the recruitment of bone marrow-derived vascular modulatory cells to regulate angiogenesis and tumor invasion. Cancer Cell. 13:206-220.
Ewald, A.J., A. Brenot, M. Duong, B.S. Chan & Z. Werb (2008). Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev. Cell. In press.
Kouros-Mehr, H., S. K. Bechis, et al. (2008). GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell. 13:141-52. PMID: 18242514 PDF
Kouros-Mehr, H., J.-W. Kim, S. K. Bechis & Z. Werb (2008). GATA-3 and the regulation of the mammary luminal cell fate. Curr. Opin. Cell Biol. PDF
Lu, P., Y. Yu, Y. Perdue & Z. Werb (2008). The apical ectodermal ridge is a timer for generating distal limb progenitors. Development. PDF
Welm, B.E., G.J.P. Dijkgraaf, A.S. Bledau, A.L. Welm & Z. Werb (2008). Lentiviral Transduction of Mammary Stem Cells for Analysis of Gene Function during Development and Cancer. Cell Stem Cell 2008 2: 90-102. PDF
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2007
Page-McCaw, A., A. J. Ewald & Z. Werb (2007). Matrix metalloproteinases and the regulation of tissue remodeling. Nat. Rev. Mol. Cell Biol. 8: 221-233. PMID: 17318226. Featured article and cover. PDF
Lemieux, G. A., F. Blumenkron, N. Yeung, P. Zhou, J. Williams, A. C. Grammer, R. Petrovich, P. E. Lipsky, M. L. Moss & Z. Werb (2007). The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J. Biol. Chem. 282:14836-14844. PMID: 17389606. PDF
Egeblad, M., H.-C. J. Shen, D. J. Behonick, L. Wilmes, A. Eichten, L. Korets, F. Kheradmand, Z. Werb & L. M. Coussens (2007). Type I collagen is a modifier of matrix metalloproteinase-2 function in skeletal development. Dev. Dyn. 236:1683-1693. [Epub Apr 17] PMID: 17440987. PDF
Lum, D.H., J. Tan, S. D. Rosen & Z. Werb (2007). Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase, Sulf2. Mol. Cell. Biol. 27:678-688. [Epub, 20 Nov 2006]. PMID: 17116694. PDF
2006
Sternlicht, M.D., H. Kouros-Mehr, P. Lu & Z. Werb (2006). Hormonal and local control of mammary branching morphogenesis. Differentiation. 74 :365-381. PDF
Kouros-Mehr, H., E. M. Slorach, M. D. Sternlicht & Z. Werb (2006). GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell 127:1041-1055. PMID: 17129787. PDF
Lu, P., M. D. Sternlicht & Z. Werb (2006). Comparative mechanisms of branching morphogenesis in diverse systems. J. Mamm. Gland Biol. Neoplasia. 11:213-228. Epub Nov 21, 2006. PMID: 17120154 . PDF
Sternlicht, M. D., A. M. Dunning, D. H. Moore, P. D. P. Pharoah, D. G. Ginzinger, K. Chin, J. W. Gray, F. M. Waldman, B. A. J. Ponder & Z. Werb (2006). Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression. Canc. Epidemiol. Biomarkers. Prev. 15: 2107-2114. PMID: 17119035. PDF
2005
Littlepage, L.E., M. Egeblad & Z. Werb (2005). Coevolution of cancer and stromal cellular responses. Cancer Cell. 7:499-500. PDF
Radisky, D. C., D. D. Levy, L. E. Littlepage, H. Liu, C. M. Nelson, J. E. Fata, D. Leake, E. L. Godden, D. G. Albertson, M.A. Nieto, Z. Werb & M. J. Bissell. (2005). Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature. 436:123-127. PDF
Sternlicht, M.D., S. W. Sunnarborg, H. Kouros-Mehr, Y. Yu, D. C. Lee & Z. Werb (2005). Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin. Development. 132:3923-3933. PDF
2004
Mott, J.D. and Z. Werb (2004). Regulation of matrix biology by matrix metalloproteinases. Curr. Opin. Cell Biol. 16: 558-564. PDF
Fata, J.E., R. Zahedi, Z. Werb & M. J. Bissell (2004). Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes. Breast Cancer Res. 6: 1-11. PDF
Ortega, N., D. J. Behonick & Z. Werb (2004). Matrix remodeling during endochondral ossification. Trends Cell Biol. 14: 86-93. PDF
